Taiwan Agricultural Research Institute, Council of Agriculture, Executive Yuan--Publication-Journal of Taiwan Agricultural Research

Journal of Taiwan Agricultural Research

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Inhibition on Osteoclasts Activity of Auricularia polytricha Extracts

Yang, S. H., H. T. Yang, and H. C. Liu. 2017. Inhibition on osteoclasts activity of Auricularia polytricha extracts. J. Taiwan Agric. Res. 66(3):261–265.

Inhibition on Osteoclasts Activity of Auricularia polytricha Extracts

Shu-Hui Yang1,*, Hui-Ting Yang2, and Hung-Chun Liu3

Abstract

    This study investigated the effect of bone metabolism and mechanism of feeding Auricularia polytricha fruiting body powder (AP) or extract (APE) on ovariectomized (OVX) rats. Female Sprague Dawley rats were divided into 3 groups, sham operated group fed on chow diet (V0), OVX fed on AP (A1) group or OVX fed on APE (A2) group. AP treatment effectively improved blood lipid values, but not significantly affected the bone metabolism. The blood biochemistry values and bone density of APE treatment can be improved to near sham operated group. APE treatment significantly increased osteoprotegerin concentration and calcium concentration of plasma on ovariectomized rats.

Key words: Auricularia polytricha powder, Auricularia polytricha extracts, Ovariectomy, Bone density, Bone-specific alkaline phosphatase, Osteoprotegerin.


* Corresponding author, email: debbie@fthes-tari.gov.tw
1 Associate Research Fellow and Head, Department of Management and Utilization, Fengshan Tropical Horticultural Experiment
Branch, Taiwan Agricultural Research Institute, Kaohsiung, Taiwan, ROC.
2 Associate Professor, Department of Nutrition, China Medical University, Taichung, Taiwan, ROC.
3 Graduate Student, Department of Nutrition, China Medical University, Taichung, Taiwan, ROC.

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