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Auricularia polytricha Extracts Improve Blood Lipid Blood Sugar Metabolism and Bone Density of Ovariectomized Rats
Bone slice of different dietary of ovariectomized rats. V0: OVX rat fed on chow diet, V1: OVX rat fed on chow diet supplemented with 0.125 g kg<sup>-1</sup> BW APE, V2: OVX rat fed on chow diet supplemented with 0.25 g kg<sup>-1</sup> BW APE, and V3: OVX rat fed on chow diet supplemented with 0.5 g kg<sup>-1</sup> BW APE.
Bone slice of different dietary of ovariectomized rats. V0: OVX rat fed on chow diet, V1: OVX rat fed on chow diet supplemented with 0.125 g kg-1 BW APE, V2: OVX rat fed on chow diet supplemented with 0.25 g kg-1 BW APE, and V3: OVX rat fed on chow diet supplemented with 0.5 g kg-1 BW APE.

Author:Hui-Ting Yang, Hung-Chun Liu, and Shu-Hui Yang*

Abstract:

    In this study, the efficacy of Auricularia polytricha extracts (APE) improving the menopausal symptoms was evaluated by an ovariectomized model. Female Sprague Dawley rats were divided into 4 groups after surgery, including OVX fed on chow diet, and OVX fed on 0.125, 0.25, or 0.5 g kg-1 APE groups. Studies have shown that OVX SD rats supplemented with APE could increase plasma HDL-C concentration, but decreased LDL-C concentration, triglyceride levels, fasting glucose and liver transaminase activity. Bone density showed correlated with APE ingesting. In short, the Auricularia polytricha extract intake can improve lipid metabolism and increase bone density on ovariectomized rats.

Key words:Auricularia polytricha extracts, Menopause, Ovariectomy, Blood biochemistry, Bone density

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